Elucidating how linear motor proteins impinge on mitochondrial morphology
نویسندگان
چکیده
منابع مشابه
on the effect of linear & non-linear texts on students comprehension and recalling
چکیده ندارد.
15 صفحه اولMitochondrial Morphology
single-peaked, tuned receptor. After allowing for the above errors, I interpret Hillman's response as a claim that my hierarchical ordering of the tuned receptor as one part of traditional color theory was inappropriate and misleading. Indeed, Hillman says that: "The essence of the PalmerYoung paradigm . . . has nothing to do [italics mine] with the shape or narrowness of these curves." This as...
متن کاملAlternative topogenesis of Mgm1 and mitochondrial morphology depend on ATP and a functional import motor
Mitochondrial morphology and inheritance of mitochondrial DNA in yeast depend on the dynamin-like GTPase Mgm1. It is present in two isoforms in the intermembrane space of mitochondria both of which are required for Mgm1 function. Limited proteolysis of the large isoform by the mitochondrial rhomboid protease Pcp1/Rbd1 generates the short isoform of Mgm1 but how this is regulated is unclear. We ...
متن کاملAppoptosin interacts with mitochondrial outer-membrane fusion proteins and regulates mitochondrial morphology.
Mitochondrial morphology is regulated by fusion and fission machinery. Impaired mitochondria dynamics cause various diseases, including Alzheimer's disease. Appoptosin (encoded by SLC25A38) is a mitochondrial carrier protein that is located in the mitochondrial inner membrane. Appoptosin overexpression causes overproduction of reactive oxygen species (ROS) and caspase-dependent apoptosis, where...
متن کاملHow defects in central tolerance impinge on a deficiency in regulatory T cells.
Both central (thymic) and peripheral (nonthymic) mechanisms are important for the induction and maintenance of T cell tolerance. Mice with a defect in Foxp3, required for the generation and activity of CD4(+)CD25(+) regulatory T cells, exhibit massive lymphoproliferation and severe inflammatory infiltration of multiple organs, in particular the lungs, liver, and skin. We have explored how this ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Bioenergetics
سال: 2016
ISSN: 0005-2728
DOI: 10.1016/j.bbabio.2016.04.416